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KMID : 0380620110430060747
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Korean Journal of Food Science and Technology
2011 Volume.43 No. 6 p.747 ~ p.753
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Hair Growth Promoting Effect of Black Soybean Extract In Vitro and In Vivo
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Jeon Hee-Young
Kim Seung-Hun
Kim Chae-Wook
Shin Hyun-Jung
Seo Dae-Bang
Lee Sang-Jun
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Abstract
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It is commonly believed that black soybean (Glycine max: BB) prevents and alleviates hair loss. However, few studies have directly assessed the effect of BB on hair growth. We presently evaluated the mitosis induction on dermal papillae cell and mitogenic effect on NIH3T3 cells in vitro. To elucidate the hair growth promoting effect in vivo, anagen induction and hair restoration were examined in a shaving model of C57BL/6 mice. We also conducted biochemical analysis of blood plasma. Significant stimulation of dermal papillae and NIH3T3 cell proliferation were observed by treatment of BB in a dose-dependent manner. BB markedly promoted hair growth and significantly improved blood total antioxidant capacity and reduced lipid peroxidation and triglyceride level. These results suggest that BB has hair growth promoting effect and it is a potent candidate for the prevention of hair loss.
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KEYWORD
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black soybean, C57BL/6 mice, hair growth promotion
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